Serotypes and genotypes of S. Pneumoniae isolates from adult invasive disease in Spain: A 5-year prospective surveillance after pediatric PCV13 licensure. The ODIN study.

Asunción Fenoll,Carmen Ardanuy,Josefina Liñares,Emilia Cercenado,Francesc Marco,Ana Fleites,María Rodríguez-Mayo, Jose-Luis López-Hontangas, Begoña Palop,Ana-Isabel Aller,Buenaventura Buendía,Cristina Méndez,Isabel Cifuentes

Vaccine（2018）

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摘要

Serotypes/genotypes causing invasive pneumococcal disease (IPD) in adults are determined by vaccination strategies. The aim of this study was to assess the epidemiology of IPD in adults (≥18 years) after PCV13 introduction for children: serotypes, clonal complexes, antibiotic non-susceptibility and clinical presentations.

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关键词

Streptococcus pneumoniae,PCV13,Serotype,Clonal complex,Invasive pneumococcal disease

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