Mutagenesis and Imaging Studies of BMP Signaling Mechanisms in C. elegans.

Methods in molecular biology (Clifton, N.J.)(2019)

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摘要
C. elegans has played a central role in the elucidation of the TGFβ pathway over the last two decades. This is due to the high conservation of the pathway components and the power of genetic and cell biological approaches applied toward understanding how the pathway signals. In Subheading 3, we detail approaches to study the BMP branch of the TGFβ pathway in C. elegans.
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关键词
Body size,C. elegans,Coelomocytes,Development,Genetic screens,Imaging,Mesoderm,Mutagenesis,Trafficking
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