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Structure-based Design and Discovery of Potent and Selective Lysine-Specific Demethylase 1 (LSD1) Inhibitors.

Zhe Nie, Lihong Shi,Chon Lai,Christophe Severin,Jiangchun Xu,Joselyn R. Del Rosario,Ryan K. Stansfield, Robert W. Cho,Toufike Kanouni,James M. Veal,Jeffrey A. Stafford,Young K. Chen

Bioorganic & Medicinal Chemistry Letters（2018）

Cited 11|Views31
Key words
Epigenetics,Demethylase,Lysine-specific demethylase 1,LSD1,Structure-based drug design
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