The imbalance of peripheral interleukin-18 and transforming growth factor-β1 levels in patients with cirrhosis and esophageal varices.

Agnieszka Swidnicka-Siergiejko,Urszula Wereszczynska-Siemiatkowska,Andrzej Siemiatkowski,Justyna Wasielica-Berger,Jacek Janica,Barbara Mroczko,Andrzej Dabrowski

Cytokine（2019）

引用 8|浏览15

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摘要

•Cirrhotics with esophageal varices have an imbalance of IL-18 and TGF-β1 levels.•Peripheral IL-18 and TGF-β1 levels correlate with liver failure indicators.•Peripheral Il-18 levels decrease with beta-blocker therapy.•Peripheral IL-18 levels can be a marker of clinically significant portal hypertension.

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关键词

PH,HSCs,KCs,NO,ET-1,TGF-β1,IL-1β,TNF- α,IL-18,MELD,HBV,HCV,TRL4,LPS

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