High-flow versus standard nasal cannula in morbidly obese patients during colonoscopy: A prospective, randomized clinical trial.

•Morbidly obese patients are at risk for hypoxemia during deep sedation.•The role of high-flow nasal cannula in anesthetic management is unclear.•No difference in desaturation rates found between HFNC and standard cannula groups.•HFNC did not prevent desaturation in morbidly obese patients under deep sedation.