Rectal Indomethacin and Spraying of Duodenal Papilla with Epinephrine Increases Risk of Pancreatitis Following Endoscopic Retrograde Cholangiopancreatography.

Hui Luo,Xiangping Wang,Rongchun Zhang,Shuhui Liang,Xiaoyu Kang, Xiaofeng Zhang,Qifeng Lou,Kangwei Xiong,Jing Yang,Lijuan Si,Wenming Liu,Yunpeng Liu,Yi Zhou, Suli Wang, Mei Yang,Wei Chen, Yanzhi Han,Guochen Shang,Xiaocui Yang,Yongfeng He, Qiang Zou,Wenwei Guo,Yichen Dai,Wei Zeng,Xiaosan Zhu, Rongqing Gong,Xun Li,Zhanguo Nie,Qi Wang,Ling Wang,Yanglin Pan,Xuegang Guo,Daiming Fan

Clinical Gastroenterology and Hepatology（2019）

Cited 34|Views19

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Abstract

In a randomized trial, we found the combination of rectal indomethacin with papillary epinephrine spraying to increase risk of PEP compared to indomethacin alone. Spray epinephrine should not be used with rectal indomethacin for prevention of post-ERCP pancreatitis. ClincialTrials.gov no: NCT03057769.

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Key words

Anti-Inflammatory,NSAIDs,Prevention,Chemoprophylaxis

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