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Immune Reconstitution and Infection Patterns Following Early Alemtuzumab and Reduced Intensity Transplantation for Non-Malignant Disorders in Pediatric Patients.

Sima T Bhatt,Jeffrey J Bednarski, Julia Berg,Kathryn Trinkaus,Lisa Murray,Robert Hayashi,Ginny Schulz,Monica Hente,Michael Grimley,Ka Wah Chan,Naynesh Kamani,David Jacobsohn,Michael Nieder,Gregory Hale,Lolie Yu,Roberta Adams,Jignesh Dalal,Michael A Pulsipher,Paul Haut,Sonali Chaudhury,Jeffrey Davis,Jennifer Jaroscak,Martin Andreansky,Jennifer Willert,Shalini Shenoy

Biology of Blood and Marrow Transplantation（2019）

Cited 11|Views65
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Abstract
•Early alemtuzumab allowed early immune recovery despite immune ablation.•Systemic infections similarly tracked immune reconstitution.•Infection patterns were similar after related and unrelated transplants.
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Key words
Stem cell transplant,Nonmalignant disorders,Immune reconstitution,Reduced-intensity conditioning
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