Transcript profiling in the testes and prostates of postnatal day 30 Sprague-Dawley rats exposed prenatally and lactationally to 2-hydroxy-4-methoxybenzophenone

Reproductive Toxicology(2018)

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摘要
•HMB exposure differentially affected transcript levels in rat prostate and testis.•Gene expression changes in response to HMB were dose and tissue type dependent.•Drug metabolism pathways were altered by HMB exposure in the prostate and testis.•HMB exposure affected apoptosis and energy metabolism pathways in the testis.
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关键词
2-hydroxy-4-methoxybenzophenone (HMB),Prostate,Testis,Rats,Gene expression profiling,Prenatal and lactational exposure,Mitochondria
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