Identification of Amino Acid Substitutions Within the VP7 Genes of G2 Rotavirus Strains in Ghana
PEDIATRIC INFECTIOUS DISEASE JOURNAL(2018)
Abstract
We used the dideoxynucleotide chain termination method to determine the strains of nine non-typeable rotavirus enzyme immunoassay–positive samples, which were identified as G2. We detected nucleotide changes in the primer-binding region and amino acid substitutions within the VP7 protein of the G2 rotavirus strains. Genotyping primers need to be updated regularly.
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Key words
Ghana,Group A rotaviruses,G2 genotype,Phylogenetic analysis
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