Insulin like growth factor binding protein 2 (IGFBP-2) for risk prediction in patients with severe aortic stenosis undergoing Transcatheter Aortic Valve Implantation (TAVI)

•Severe aortic stenosis (AS) is the most frequent acquired valvular heart disease worldwide and mortality rates are considerably high.•Transcatheter Aortic Valve Implantation (TAVI) is a well-established method for valve replacement in high risk patients with AS.•There is a lack of reliable predictors for patients undergoing TAVI since commonly used scores were developed for surgical populations.•Here we show that IGFBP-2 could serve as new outcome predictor for patients undergoing TAVI procedure.