[Study on the mechanism of hypertonic salt solution alleviates lung injury of rats at the early stage of severe scald].
Zhonghua wei zhong bing ji jiu yi xue(2018)
摘要
HS protected against lung injury induced by severe burns in rats with a dose-dependent manner, and it was better than LR, and its possible mechanism was related with reducing the expression of p38MAPK and ERK1/2 pathway in lung tissue, increasing the level of anti-inflammatory cytokines and decreasing the release of pro-inflammatory cytokines, thus inhibiting excessive inflammation and oxidative stress injury in lung.
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关键词
Scald,Hypertonic salt solusion,Lung,Interleukin,Signal transduction pathway
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