Mainly post-transplant factors are associated with invasive aspergillosis after allogeneic stem cell transplantation. A study from the SAIF and SFGM-TC.

•This was the largest series of invasive aspergillosis in allogeneic HCT patients in Europe.•Most cases (63%) were observed after day 100, making IA a late complication of HCT.•The risk of IA was associated with post-transplant factors whatever the date of onset.•IA occurrence cannot be reliably predicted before transplant.•GVHD, secondary neutropenia, and relapse remain associated with IA in the RIC era.