Weighted gene co-expression network analysis and connectivity map identifies lovastatin as a treatment option of gastric cancer by inhibiting HDAC2.
Gene(2019)
Abstract
•This study aimed to identifying and validating therapeutic compounds.•HDAC2 was overexpressed in gastric cancer cell lines.•For treating GC, lovastatin may be a potential drug.
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Key words
CCK-8,CMap,DAKO,DMSO,FC,GC,GEO,HDAC,QRT-PCR,TOM,V,VPA,WGCNA
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