GABAergic inhibition reduces the impact of synaptic excitation on somatic excitation.

Chiaki Kobayashi,Kazuki Okamoto,Yasuhiro Mochizuki,Hidetoshi Urakubo,Kenta Funayama,Tomoe Ishikawa,Tetsuhiko Kashima,Ayako Ouchi,Agnieszka F Szymanska,Shin Ishii,Yuji Ikegaya

Neuroscience Research（2019）

引用 4|浏览25

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摘要

•A high-speed, large-scale calcium imaging monitors excitatory synaptic inputs from hundreds of spines in a single neuron.•Approximately half of the excitatory synaptic inputs fail to excite the cell body.•Local GABAergic inhibition invalidates these excitatory inputs.•GABAergic inhibition allows dendrites to filter inputs from presynaptic cell assemblies.

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AP5,CNQX,ECl−

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