Betulinic acid protects mice from cadmium chloride-induced toxicity by inhibiting cadmium-induced apoptosis in kidney and liver.

Rong Fan,Peng-Chao Hu, Ying Wang,Hong-Yi Lin,Ke Su,Xue-Song Feng,Lei Wei,Fang Yang

Toxicology Letters（2018）

引用 60|浏览18

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摘要

•Betulinic acid decreases the toxicity of cadmium chloride.•Betulinic acid prevents cadmium chloride-induced increase of serum AST, ALT and BUN.•Betulinic acid reduces residual cadmium level and promotes cadmium excretion.•Betulinic acid alleviates the kidney and testis damage induced by cadmium.

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关键词

BA,Cd,ALT,AST,BUN,ELISA,Bcl-2,Bax,EDTA,DDTC,ROS,TNF-α,TGF-β,PTFE,RSD,GF-AAS,H&E,BCA,SDS-PAGE,PVDF,GAPDH,TBST,HRP,ECL,SPSS,SEM,SD

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