Complement Regulatory Genetic Mutations in the Setting of Autoimmune Thrombotic Thrombocytopenic Purpura: A Case Series.

Shebli Atrash,Appalanaidu Sasapu,Soumya Pandey,Michele Cottler-Fox,Pooja Motwani

Mayo Clinic Proceedings: Innovations, Quality & Outcomes（2018）

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摘要

We found eculizumab therapy to be effective in all 3 patients. However, its efficacy was prominent only after clearance of antibodies against ADAMTS13 via therapeutic plasma exchange.

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关键词

ADAMTS13,aHUS,BU,CF,CFHR,HUS,iTTP,TMA,TPE,TTP

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