Structural analysis and anthelmintic activity of Canavalia brasiliensis lectin reveal molecular correlation between the carbohydrate recognition domain and glycans of Haemonchus contortus.

Molecular and Biochemical Parasitology(2018)

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摘要
•ConBr showed significant inhibition of H. contortus larval development.•Molecular docking revealed that glycans interact in the carbohydrate recognition domain of ConBr.•ConBr may be an alternative in the control of helminths.
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关键词
ConBr,Molecular docking,Core trimannoside,Parasite,Anthelmintic activity
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