Plant lyophilisate carrying S-HBsAg as an oral booster vaccine against HBV.
Vaccine（2018）
Abstract
•Plant lyophilisate with low-dosed S-HBsAg is effective as oral booster vaccine.•Injection priming and then 2×p.o. boosting is comparably efficient as 3×i.m. vaccination.•Oral administration of plant lyophilisate is effectual without exogenous adjuvants.
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Key words
HBV,Oral booster vaccine,Injection-oral immunisation,Lyophilisate,Plant-derived vaccine,S-HBsAg
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