Complement 5a Receptor Polymorphisms Are Associated With Panton-Valentine Leukocidin-positive Staphylococcus aureus Colonization in African Pygmies.

Frieder Schaumburg,Anika Witten,Arnaud Flamen,Monika Stoll,Abraham S Alabi,Peter G Kremsner,Bettina Löffler, Peter F Zipfel,Thirumalaisamy P Velavan,Georg Peters

CLINICAL INFECTIOUS DISEASES（2019）

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摘要

Panton-Valentine leukocidin (PVL) is common in African Staphylococcus aureus and can be associated with skin and soft tissue infection. PVL-positive S. aureus colonization is associated with a variant of complement receptor 5a, the cellular target of the lukS PVL subunit.

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关键词

Staphylococcus aureus,complement C5a,receptor,Panton-Valentine leukocidin,polymorphism

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