Effects of Klotho polymorphisms on Preeclampsia risk in a case-control study.

•Preeclampsia (PE) is a pregnancy-specific syndrome that may be lifethreatening to mothers and fetus.•Although extensive researches have been made for many years, the etiology and pathophysiology remains unclear.•This study investigated the polymorphisms of Klotho and the susceptibility to PE whose findings may be significant to clarify the pathogenesis of PE.