Reticular rash in drug reaction with eosinophilia and systemic symptoms syndrome: A clue to parvovirus B19 reactivation?

The term drug reaction with eosinophilia and systemic symptoms (DRESS) refers to a complex syndrome characterized by cutaneous lesions, eosinophilia, and systemic symptoms that may be triggered by different medications. The reaction takes place 2 to 6 weeks after the initial exposure to the culprit drug.1 Even after appropriate diagnosis and treatment have been conducted, patients may experience isolated or sequential relapses and slow clinical resolution that may be associated with viral reactivations of herpesvirus.