KIR Donor Selection: Feasibility in Identifying Better Donors.

Daniel Weisdorf,Sarah Cooley,Tao Wang,Elizabeth Trachtenberg,Michael D Haagenson,Cynthia Vierra-Green,Stephen Spellman,Ashley Spahn,Jenny Vogel, Hati Kobusingye, Todd Fehninger,Ann Woolfrey,Steven Devine,Maureen Ross,Edmund K Waller,Ronald Sobecks,Peter Parham,Lisbeth A Guethlein,Steven Ge Marsh,Jeffrey Miller

Biology of Blood and Marrow Transplantation（2019）

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摘要

•Favorable killer cell immunoglobulin-type receptor unrelated donors for transplantation may improve outcome.•Prospective testing did not enrich the donor options with favorable donors: too few were genotyped.•Donor search relying on additional factors beyond HLA may require extra effort and more donors considered.

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关键词

Allogeneic hematopoietic cell transplant,Unrelated donor selection,KIR,HLA

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