Pharmacokinetic herb–drug interaction of Xuesaitong dispersible tablet and aspirin after oral administration in blood stasis model rats

Guoliang Dai,Zhitao Jiang,Yongtao Bai,Qian Zhang,Lei Zhu,Xiaohui Bai,Wenzheng Ju,Ronghua Pan

Phytomedicine（2017）

引用 17|浏览6

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摘要

It showed that that apparent herb—drug pharmacokinetic interaction existed between aspirin and Xuesaitong dispersible tablet, and the combination of aspirin and Xuesaitong dispersible tablet noticeably altered the absorption, distribution and disposition of Rg1 and R1.Image, graphical abstract

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关键词

Xuesaitong dispersible tablet,Aspirin,Pharmacokinetics,Herb–drug interaction,UHPLC-MS/MS

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