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Clinically proven drug targets differentially expressed in the prefrontal cortex of schizophrenia patients.

Joanne Voisey,Divya Mehta,Robert McLeay,Charles P Morris,Leesa F Wockner,Ernest P Noble,Bruce R Lawford,Ross McD Young

Brain, Behavior, and Immunity（2017）

Cited 5|Views7
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Abstract
•1146 genes are differentially expressed in schizophrenia.•A strong pattern of differentially expressed immune response genes.•23 genes are clinically proven drug targets as well as 20 antipsychotic agents.•16 genes are associated with schizophrenia from the Psychiatric Genomics Consortium.
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Key words
Brain,Schizophrenia,Gene expression,RNA-Seq,Methylation,Immune response
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