Human acellular dermis increases surgical site infection and overall complication profile when compared with submuscular breast reconstruction: An updated meta-analysis incorporating new products ✰ .

This study suggests an increased risk of overall complications, specifically infection and flap necrosis, in patients who underwent tissue expander/implant breast reconstruction with HADM when compared with those who underwent submuscular placement. This must be weighed against the advantages in enhancing aesthetic outcomes, increasing intraoperative fill volume, and ameliorating capsular contracture.