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Different amplification patterns of 3q26 and 5p15 regions in cervical intraepithelial neoplasia and cervical cancer.

Erik Kudela,Jozef Visnovsky,Tomas Balharek,Anna Farkasova,Pavol Zubor,Lukas Plank,Jan Danko

Annals of Diagnostic Pathology（2018）

Cited 7|Views10
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Abstract
•We focused on amplification patterns of chromosomal regions 3q26 and 5p15 connected with the telomerase activity.•Telomerase activity could be a valuable marker for the diagnosis of cervical neoplasia.•The amplification of 3q26 and 5p15 regions may serve in the future for the differential diagnosis of cervical lesions.
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Key words
Cervical intraepithelial neoplasia,Telomerase,Amplification,Fluorescent in situ hybridization,TERC,TERT
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