In vivo imaging reveals increased eosinophil uptake in the lungs of obese asthmatics.

Neda Farahi,Chrystalla Loutsios,Nicola Tregay,Adam K A Wright,Rachid Berair,Laurence S C Lok,Daniel Gillett,Ian Cullum,Rosalind P Simmonds,Charlotte Summers,Anna Wong,Chandra K Solanki,John Buscombe,Pee Hwee Pang, Arthikkaa Thavakumar, A Michael Peters,Christopher E Brightling,Alison M Condliffe,Edwin R Chilvers

Journal of Allergy and Clinical Immunology（2018）

引用 28|浏览20

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摘要

Using radiolabeled eosinophils coupled with SPECT/CT the authors quantify eosinophilic inflammation in the lungs of patients with asthma and focal pulmonary eosinophilic inflammation, revealing important differences in eosinophil kinetics between obese and non-obese asthmatics.

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关键词

SPECT/CT,asthma,eosinophils,obesity

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