Mixed surfactant (altering chain length and head group) aggregates as an effective carrier for tuberculosis drug

Chemistry and Physics of Lipids(2018)

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摘要
•Mixed surfactant aggregates were prepared and characterized.•Rifampicin solubilization was comparatively analyzed and improved.•Rifampicin was stabilized in highly basic medium and in strong oxidizing condition.•Interaction site of rifampicin within aggregates was evaluated.
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关键词
Anti-tuberculosis drug,Aqueous solubility,Drug stability,Mixed surfactant aggregates,Drug-surfactant interactions
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