Association of serum uric acid with bone mineral density and clinical fractures in Chinese type 2 diabetes mellitus patients: A cross-sectional study.

Clinica Chimica Acta(2018)

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摘要
•T2DM patients with osteoporosis had lower serum UA levels compared with those with normal BMD values and osteopenia (all P < 0.01).•Serum UA level was significantly correlated with BMD values at each site in postmenopausal women, and was positively associated with BMD values at the lumbar spine in men (P < 0.01 or P < 0.05).•Patients with clinical fractures had lower serum UA than those without (P < 0.01 or P < 0.05).•Multiple logistic regression analysis showed that serum UA levels were significantly and inversely associated with the presence of diabetic osteoporotic fractures independently of all risk factors except for BMD values at each site.
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关键词
Serum uric acid,Bone mineral density,Clinical fractures,Osteoporosis,Type 2 diabetes mellitus
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