Local delivery of thalidomide to inhibit neointima formation in rat model with artery injury.

Shougang Sun,Quan Zhang,Qiongying Wang,Qiang Wu,Guangli Xu,Peng Chang,Hao Hu,Feng Bai

Pathology - Research and Practice（2018）

引用 5|浏览20

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摘要

Thalidomide, which is a specific VEGF inhibitor, significantly inhibited neointimal hyperplasia and vascular restenosis after balloon injury to the carotid artery in rats, thus potentially providing a novel method for the prevention and treatment of restenosis, especially in-stent restenosis.

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关键词

PTCA,VEGF,TNF-α,ELISA,RT-PCR,DES,SMC,EEL area,IEL area

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