Epigallocatechin-3-gallate promotes apoptosis and reversal of multidrug resistance in esophageal cancer cells.

Liang Liu,Yingchao Ju,Jing Wang,Rongmiao Zhou

Pathology - Research and Practice（2017）

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摘要

•EGCG inhibited cell growth and induced esophageal cancer cell apoptosis.•EGCG modulated bcl-2, bax and caspase-3 protein of esophageal cancer cells.•EGCG reversed multi-drug resistance by reducing ABCG2 expression in cancer cells.

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关键词

Esophageal squamous cell carcinoma,Flow cytometry,Epigallocatechin-3- gallate,Cell apoptosis,Multidrug resistance

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