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Structure of an extended β3 integrin

Dongwen Zhou,Aye Myat Myat Thinn,Yan Zhao,Zhengli Wang,Jieqing Zhu

Blood（2018）

Cited 15|Views12
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Abstract
Key Points Conformational extension is essential for integrin to fulfill its cell-adhesion function in platelet-mediated hemostasis and thrombosis. High-resolution structures of β3 integrin in intermediate and extended conformations reveal atomic-level conformational rearrangements.
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extended β3 integrin
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