Pentraxin 3 and biopsy status in celiac patients.

Gastroenterology and hepatology from bed to bench（2018）

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摘要

PTX3 is a component of the humoral arm of the innate immune system. Our data showed that PTX3 serum levels were high in active disease patients with pathological levels of AGA. We also demonstrated that patients with normal AGA IgA levels had PTX3 serum levels compared to healthy control. We hypothesized that PTX3 is able to modulate the innate response to gliadin in CD and it could regulate the adaptive immune response.

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关键词

Adaptive immune response,Antigliadin antibodies,Celiac disease,Gluten-sensitivity,Innate immune response,Pentraxin 3

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