Management of melanoma in patients with chronic lymphocytic leukemia
Leukemia Research(2018)
Abstract
•CLL patients have a significantly higher risk of invasive melanoma.•Most melanomas (68.2%) were detected through active surveillance in a dermatology clinic.•Most melanomas (77.3%) were detected at a non-advanced stage.•Active surveillance for melanoma leading to early excision could be beneficial.•Ibrutinib and pembrolizumab was effective therapy for progressive CLL and metastatic melanoma.
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Key words
Chronic lymphocytic leukemia,Small lymphocytic lymphoma,CLL,Melanoma,Immune checkpoint inhibitors,Pembrolizumab,PD-1 inhibitor
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