The anti-inflammatory and anti-oxidative actions of eugenol improve lipopolysaccharide-induced lung injury.

•BALB/c mice got saline (0.05 mL) or 10 μg of lipopolysaccharide into the trachea.•A dose-response curve for eugenol treatment (15–1500 mg/kg) was done 6 h after LPS.•Other mice (same protocol) received the lower effective eugenol dose (150 mg/kg).•Anti-inflammatory and anti-oxidant actions of eugenol were tested in these mice.•Eugenol improved LPS-triggered lung injury as anti-inflammatory and anti-oxidant.