LRRK2 G2019S Parkinson's disease with more benign phenotype than idiopathic.

Sawssan Ben Romdhan,Nouha Farhat,Amina Nasri,Suzanne Lesage,Olfa Hdiji,Mouna Ben Djebara,Zied Landoulsi,Giovanni Stevanin,Alexis Brice,Mariem Damak,Riadh Gouider,Chokri Mhiri

Acta neurologica Scandinavica（2018）

引用 19|浏览7

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摘要

In this study, G2019S carriers had a more benign phenotype than non-carriers. Cognitive impairment and depression were less common in G2019S male carriers compared with females. In addition, we found that LRRK2 gene dosage does not influence the severity of PD.

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关键词

G2019S mutation,Parkinson's disease,phenotype

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