Low serum 25-hydroxyvitamin D concentrations in chronic insomnia patients and the association with poor treatment outcome at 2months.
Clinica Chimica Acta(2017)
摘要
•Serum 25(OH)D concentrations in chronic insomnia patients were significantly lower than those of healthy control subjects.•Non-response patients had significantly lower 25(OH)D concentrations than response patients.•Vitamin D deficiency was independently associated with higher probability of treatment non-response at 2 months.•Measurement of serum 25(OH)D concentrations are probably useful for judging treatment outcomes of pharmacotherapy in chronic insomnia patients.
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关键词
25(OH)D,PSQI,GAD-7,PHQ-9,IQR
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