Amelogenin induces M2 macrophage polarisation via PGE2/cAMP signalling pathway.
Archives of Oral Biology(2017)
摘要
•Amelogenin regulates the expression of inflammatory response genes in macrophages.•Amelogenin can reprogram macrophages towards an anti-inflammatory M2 phenotype.•Amelogenin induced M2 macrophage polarization via PGE2/cAMP signalling pathway.
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关键词
Amelogenin,Enamel matrix derivative,Macrophage,Microarray,Prostaglandin E2
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