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Assessment of structurally modified plant virus as a novel adjuvant in toxicity studies

N.A. Nikitin,V.A. Zenin,E.A. Trifonova,E.M. Ryabchevskaya,O.A. Kondakova,A.N. Fedorov,J.G. Atabekov,O.V. Karpova

Regulatory Toxicology and Pharmacology（2018）

Cited 20|Views14
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Abstract
Spherical particles (SPs) generated by thermally denatured tobacco mosaic virus (TMV) coat protein can act as an adjuvant, as they are able to enhance the magnitude and longevity of immune responses to different antigens.
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Key words
Plant virus,Structurally modified virus,Tobacco mosaic virus,Spherical particles,Adjuvant,Toxicity
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