Accuracy of Sensititre YeastOne Echinocandins Epidemiological Cut-off Values for Identification of FKS mutant Candida albicans and Candida glabrata: A Ten Year National Survey of the Fungal Infection Network of Switzerland (FUNGINOS).

A Kritikos,D Neofytos,N Khanna, P W Schreiber,K Boggian, J Bille,J Schrenzel,K Mühlethaler,R Zbinden,T Bruderer, D Goldenberger,G Pfyffer,A Conen,C Van Delden, S Zimmerli,D Sanglard,D Bachmann,O Marchetti,F Lamoth

Clinical Microbiology and Infection（2018）

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摘要

This 10-year nationwide survey showed that the rate of echinocandin resistance among C. albicans and C. glabrata remains low in Switzerland despite increased echinocandin use. SYO-ECV could discriminate FKS mutants from wild-type isolates tested by SYO in this population.

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关键词

Anidulafungin,Antifungal susceptibility testing,Candidaemia,Caspofungin,FKS hotspot,Micafungin,Minimal inhibitory concentration

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