Association of fibrotic remodeling and cytokines/chemokines content in epicardial adipose tissue with atrial myocardial fibrosis in patients with atrial fibrillation.
Heart Rhythm(2018)
Abstract
Our study demonstrated that fibrotic remodeling and cytokines/chemokines in peri-LA EAT were associated with atrial myocardial fibrosis as a substrate of AF. Our results also suggested that overexpression of Hif-1α and Angptl2 may be involved in these processes.
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Key words
Atrial fibrillation,Atrial myocardial fibrosis,Epicardial adipose tissue,Inflammation,Pathology
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