Clinical validation of the Tempus xO assay.
Oncotarget(2018)
摘要
We have developed a clinically validated NGS assay that includes tumor, germline and RNA sequencing. We apply this assay to clinical specimens and cell lines, and we demonstrate a clinical sensitivity of 98.4% and positive predictive value of 100% for the clinically actionable variants measured by the assay. We also demonstrate highly accurate copy number measurements and gene rearrangement identification.
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关键词
Tempus,cancer,gene panel,genomic test,transcriptome
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