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Histological Observation of Teratogenic Phenotypes Induced in Frog Embryo Assays.

Mark E Pownall,Margaret S Saha

TERATOGENICITY TESTING: METHODS AND PROTOCOLS（2018）

Cited 3|Views1
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Abstract
Amphibian embryos have long served as an ideal model for teratogenicity testing. While whole-mount embryo observations can be utilized, histological observation of teratogenic phenotypes provides a wealth of additional information that can lead to mechanistic insights. In this chapter, detailed protocols for two methods of sectioning embryos as well as a guide for histological analysis is provided.
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Key words
Cryosectioning,Embryo,FETAX,Histology,Paraffin sectioning,Sectioning,Teratogen,Toxicology,Xenopus
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