Identification, Characterization, Immunolocalization, and Biological Activity of Lucilin Peptide

•A cecropin-like peptide genetic sequence, tissue production, and secretion in Lucilia eximia is reported.•The Lucilin peptide is active against E. coli DH10B and clinical isolates of E. coli ESBL and Enterobacter cloacae with no toxic activity on human erythrocytes and Vero cells.•The Lucilin peptide showed neutralizing activity against the TNF-α production in PBMCs stimulated with LPS and induce cellular migration on human keratinocytes.