Biological effects of mixed-ion beams. Part 1: Effect of irradiation of the CHO-K1 cells with a mixed-ion beam containing the carbon and oxygen ions.

Joanna Czub,Dariusz Banaś,Janusz Braziewicz,Iwona Buraczewska,Marian Jaskóła,Urszula Kaźmierczak,Andrzej Korman,Anna Lankoff,Halina Lisowska,Zygmunt Szefliński,Maria Wojewódzka,Andrzej Wójcik

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine（2018）

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摘要

Carbon and oxygen ions were accelerated simultaneously to estimate the effect of irradiation of living cells with the two different ions. This mixed ion beam was used to irradiate the CHO-K1 cells, and a survival test was performed. The type of the effect of the mixed ion beam on the cells was determined with the isobologram method, whereby survival curves for irradiations with individual ion beams were also used. An additive effect of irradiation with the two ions was found.

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