Nano-Pulse Stimulation is a physical modality that can trigger immunogenic tumor cell death.

Richard Nuccitelli,Amanda McDaniel,Snjezana Anand,John Cha,Zachary Mallon,Jon Casey Berridge,Darrin Uecker

Journal for immunotherapy of cancer（2017）

引用 76|浏览9

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摘要

Nano-Pulse Stimulation treatment at specific energies was able to trigger the emission of three key DAMPs at levels comparable to Doxorubicin and Mitoxantrone, two known inducers of immunogenic cell death (ICD). Therefore NPS is a physical modality that can trigger immunogenic cell death in tumor cells.

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关键词

ATP,Anthracyclines,Apoptosis,Calreticulin,Caspase,Ecto-calreticulin,HMGB1,NPS,Nano-pulse stimulation

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