Reduced transmission of Mycobacterium africanum compared to Mycobacterium tuberculosis in urban West Africa

Prince Asare,Adwoa Asante-Poku,Diana Ahu Prah,Sonia Borrell,Stephen Osei-Wusu,Isaac Darko Otchere,Audrey Forson, Gloria Adjapong,Kwadwo Ansah Koram,Sebastien Gagneux,Dorothy Yeboah-Manu

International Journal of Infectious Diseases（2018）

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摘要

•The estimated recent tuberculosis (TB) transmission rate (clustering rate of 41.2%) was found to be high in Ghana.•There is a need for increased TB awareness by the national tuberculosis control program.•Mycobacterium africanum (MAF) transmits at a lower rate compared to Mycobacterium tuberculosis in Ghana.•The incidence of MAF remained fairly constant over the study years.•Other factors may likely be responsible for maintaining MAF in West Africa.

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关键词

Mycobacterium tuberculosis,Mycobacterium africanum,Transmission,Molecular epidemiology,MIRU-VNTR,Spoligotyping

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