MiR-214 promotes cell meastasis and inhibites apoptosis of esophageal squamous cell carcinoma via PI3K/AKT/mTOR signaling pathway.

Qiao Guanen,Shi Junjie, Wu Baolin, Wang Chaoyang, Yang Yajuan,Li Jing,Li Junpeng,Ning Gaili, Wang Zhongping, Wang Jun

Biomedicine & Pharmacotherapy（2018）

引用 37|浏览3

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摘要

•MiR-214 serve as a tumor promoter regulating cells migration, invasion and apoptosis in ESCC.•LZTS1 has been proved to as a functional target for miR-214 to regulate cells poliferation and apoptosis.•MiR-214 promotes proliferation, migration, invasion and inhibits apoptosis of ESCC cells by PI3K/AKT/mTOR signaling pathway via targeting LZTS1.

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关键词

MiR-214,Meastasis,Apoptosis,PI3K/AKT/mTOR pathway,ESCC

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