In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers.

Toxicology Letters(2018)

Cited 13|Views17
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Abstract
•Tert-butylpyridinium propane regioisomers are pharmacologically characterized.•The pharmacology of the tested regioisomers is relatively comparable.•The different methods allow an insight into the receptor-mediated interactions.
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Key words
CNS,mAChR,MB327,nAChR,NMG,OPC(s),PAM(s),PNS,SSM,SURFE2R,PTM0001,PTM0002,PTM0045,Tris
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