Quantitative contrast-enhanced ultrasound evaluation of pathological complete response in patients with locally advanced breast cancer receiving neoadjuvant chemotherapy.

•PEAK, PEAK%, TTP% and diameter% were significant independent predictors of pCR, and the area under the ROC curve was 0.932(Az1).•The area under the ROC curve for quantitative parameters was 0.927(Az2).•For diameter%, the area under the ROC curve was 0.786 (Az3).•The values of Az1 and Az2 were significantly higher than that for Az3 (p = .027 and p = .034, respectively).